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ЖУРНАЛЫ // Mendeleev Communications // Архив

Mendeleev Commun., 2020, том 30, выпуск 2, страницы 183–184 (Mi mendc1141)

Эта публикация цитируется в 4 статьях

Communications

Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system

E. G. Paronikyan, Sh. Sh. Dashyan, S. S. Mamyan

Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia, Yerevan, Armenia


Аннотация: New effective synthesis of functionalized pyrano[3,4-c]thieno-[3,2-e][1,2,4]triazolo[4,3-a]pyridines comprises nucleophilic substitution in 8-morpholino-6-thioxopyrano[3,4-c]pyridine-5-carbonitrile with hydrazine hydrate followed by sequential heterocyclization with formic acid and chloroacetic acid derivatives.

Ключевые слова: pyrano[3,4-c]pyridines, triazolo[4,3-a]pyridines, pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, hydrazines, thiones, heterocyclization, alkylation.

Язык публикации: английский

DOI: 10.1016/j.mencom.2020.03.017



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