Y. Zhang, J. Bai, S. Sun, “Copper(ii)-catalyzed three-component coupling sequence for the efficient synthesis of 2-arylquinolines: 1,4-dioxane serving as the C2 building block”, Mendeleev Commun., 34:3 (2024), 401

Communications

Copper(ii)-catalyzed three-component coupling sequence for the efficient synthesis of 2-arylquinolines: 1,4-dioxane serving as the C₂ building block

Y. Zhang^a, J. Bai^b, S. Sun^b

^a Suzhou Industrial Park Institute of Services and Outsourcing, Suzhou, Jiangsu, China
^b School of Petrochemical Engineering, Changzhou University, Changzhou, China

Аннотация: A copper-catalyzed three-component coupling sequence for 2-arylquinolines formation from aromatic aldehydes, anilines and 1,4-dioxane has been described. Unexpectedly, 1,4-dioxane served as a C₂ building block in this transformation. This formal [4 + 2] approach provides rapid access to 2-arylquinolines with broad substrate scope under mild conditions.

Ключевые слова: three-component coupling reaction, copper catalysis, 1,4-dioxane, C₂ building block, cycloaddition, quinolines.

Язык публикации: английский

DOI: 10.1016/j.mencom.2024.04.028

	*Дополнительные материалы:*
		Supplementary_data_1.pdf	1.3 Mb