R. F. Fatykhov, M. I. Savchuk, E. S. Starnovskaya, M. V. Bobkina, D. S. Kopchuk, E. V. Nosova, G. V. Zyryanov, I. A. Khalymbadzha, O. N. Chupakhin, V. N. Charushin, V. G. Kartsev, “Nucleophilic substitution of hydrogen–the Boger reaction sequence as an approach towards 8-(pyridin-2-yl)coumarins”, Mendeleev Commun., 2019, том 29, выпуск 3,страницы 299

Эта публикация цитируется в 24 статьях

Communications

Nucleophilic substitution of hydrogen–the Boger reaction sequence as an approach towards 8-(pyridin-2-yl)coumarins

R. F. Fatykhov^a, M. I. Savchuk^a, E. S. Starnovskaya^a, M. V. Bobkina^a, D. S. Kopchuk^ab, E. V. Nosova^ab, G. V. Zyryanov^ab, I. A. Khalymbadzha^ab, O. N. Chupakhin^ab, V. N. Charushin^ab, V. G. Kartsev^c

^a Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
^b I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^c 'InterBioScreen Ltd.', Chernogolovka, Moscow Region, Russian Federation

Аннотация: 5,7-Dimethoxy-8-(3,6-diphenylpyridin-2-yl)coumarins were obtained from 5,7-dimethoxycoumarins and 3,6-diphenyl-1,2,4-triazines via the protocol comprising aromatic $\mathrm{S_N^H}$ substitution in the triazine ring followed by the Boger transformation of formed triazine moiety into the pyridine one. The advantages of the suggested method are simple procedures, high yields, and the absence of transition-metal catalysts.

Язык публикации: английский

DOI: 10.1016/j.mencom.2019.05.019

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