Mechanism of formation of adsorption complexes amikacin–detonation nanodiamond

The adsorption of amikacin on the surface of detonation nanodiamonds was revealed as proceeding via the Coulomb or donor–acceptor interactions depending on the functional composition of the nanodiamond surface. In the case of nanodiamonds with carboxyl groups on their surface, the complexes were formed through the Coulomb interactions, while the donor–acceptor mechanism was realized in the presence of nitrate ions on the surface.