A. S. Kucherenko, V. V. Perepelkin, G. M. Zhdankina, G. V. Kryshtal', E. Srinivasan, H. Inani, S. G. Zlotin, “Ionic liquid supported 4-HO-Pro-Val derived organocatalysts for asymmetric aldol reactions in the presence of water”, Mendeleev Commun., 2016, том 26, выпуск 5,страницы 388

Эта публикация цитируется в 17 статьях

Ionic liquid supported 4-HO-Pro-Val derived organocatalysts for asymmetric aldol reactions in the presence of water

A. S. Kucherenko^a, V. V. Perepelkin^a, G. M. Zhdankina^a, G. V. Kryshtal'^a, E. Srinivasan^b, H. Inani^b, S. G. Zlotin^a

^a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Rajasthan, India

Аннотация: Novel (4R)-HO-(2S)-Pro-(S)-Val derivative tagged to 1-methylimidazolium cation and PF₆^– anion efficiently catalyzes asymmetric aldol reactions of cyclic ketones with aromatic aldehydes in aqueous environment to afford the corresponding aldols in high yield with moderate to high anti-diastereo- (dr up to 99 : 1) and enantioselectivity (up to 98% ee). The catalyst was recycled 9 times in the same reaction without any decrease in selectivity values.

Язык публикации: английский

DOI: 10.1016/j.mencom.2016.09.007