D. S. Kopchuk, I. S. Kovalev, A. F. Khasanov, G. V. Zyryanov, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin, “A rational protocol for the synthesis of 1-(2-pyridyl)isoquinolines”, Mendeleev Commun., 23:3 (2013), 142

Эта публикация цитируется в 19 статьях

Communications

A rational protocol for the synthesis of 1-(2-pyridyl)isoquinolines

D. S. Kopchuk^ab, I. S. Kovalev^a, A. F. Khasanov^a, G. V. Zyryanov^ab, P. A. Slepukhin^b, V. L. Rusinov^ab, O. N. Chupakhin^ab

^a Department of Chemistry, Ural Federal University, Ekaterinburg, Russian Federation
^b I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation

Аннотация: Aza-Diels–Alder reaction between 3-(2-pyridyl)-1,2,4-triazines and 1-morpholinocyclohexene followed by aromatization of the cyclohexene moiety affords 1-(2-pyridyl)isoquinolines. Crystal structures of two tetrahydroisoquinolines were confirmed by X-ray diffraction analysis.

Язык публикации: английский

DOI: 10.1016/j.mencom.2013.05.007

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