Synthesis of regioisomeric (S)-(+)-3,3,4-trimethyl-8-methoxy-3,4-dihydrobenzo[h]isoquinolin-1(2H)-one and (S)-(+)-1,2,2-trimethyl-8-methoxy-1,2-dihydrobenzo[f]isoquinolin-4(3H)-one by the Ritter reaction
Аннотация:
The conservation of chirality at the α-position to the carbocationic centre of (S)-(–)-2-methyl-3-(6-methoxynaphth-2-yl)butan-2-ol and the formation of regioisomeric (S)-(+)-1,2,2-trimethyl-8-methoxy-1,2-dihydrobenzo[f]isoquinolin-4(3H)-one were found in the synthesis of (S)-(+)-3,3,4-trimethyl-8-methoxy-3,4-dihydrobenzo[h]isoquinolin-1(2H)-one by the Ritter reaction.