R. G. Kostyanovsky, K. A. Lyssenko, G. K. Kadorkina, O. V. Lebedev, A. N. Kravchenko, I. I. Chervin, V. R. Kostyanovsky, “Chiral glycouril, 2,6-diethyl-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-dione: spontaneous resolution, reactivity and absolute configuration”, Mendeleev Commun., 1998, том 8, выпуск 6,страницы 231

Эта публикация цитируется в 27 статьях

Chiral glycouril, 2,6-diethyl-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-dione: spontaneous resolution, reactivity and absolute configuration

R. G. Kostyanovsky^a, K. A. Lyssenko^b, G. K. Kadorkina^a, O. V. Lebedev^c, A. N. Kravchenko^c, I. I. Chervin^a, V. R. Kostyanovsky^a

^a N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Moscow, Russian Federation
^b A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^c N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Аннотация: The title glycouril 1 was spontaneously resolved into enantiomers by crystallisation from H₂O and sorting of conglomerate crystals, then N-chlorination and N-aminomethylation to give 2,3 and 4, respectively, were studied. The absolute configuration 1R,5R-(+) was determined by an X-ray diffraction study of diastereomeric N,N-bis-aminomethyl derivative (—)-4.

Язык публикации: английский

DOI: 10.1070/MC1998v008n06ABEH001035