Stannous lodide–HCI in Tetrahydrofuran: A New System for the Reduction of various Nitro Compounds. Mild Conversion of 6-Nitro-Δ5-Steroids to 6-Keto-steroids
aNatural Products Chemistry Group, Regional Research Laboratory, Assam, India bAtul Chemicals, Valsad, Gujrat, India cRRL Bhubaneswar, Bhubaneswar, Orissa, India dPhytochemistry Division, CIMAP, Lucknow, India
Аннотация:
It has been shown that 6-nitro-Δ5-steroids, nitrostyrene and saturated aliphatic nitro compounds in tetrahydrofuran are reduced efficiently with stannous iodide and a catalytic amount of concentrated hydrochloric acid to the corresponding 6-ketosteroids, oximes or hydroxylamine derivatives in good yields, respectively.
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