O. V. Tsepaeva, A. V. Nemtarev, A. V. Kundina, L. R. Grigor’eva, V. F. Mironov, “Synthesis of novel mannopyranosyl betulinic acid phosphoniohexyl ester”, Mendeleev Commun., 2021, том 31, выпуск 1,страницы 110

Эта публикация цитируется в 3 статьях

Synthesis of novel mannopyranosyl betulinic acid phosphoniohexyl ester

O. V. Tsepaeva^a, A. V. Nemtarev^ab, A. V. Kundina^b, L. R. Grigor’eva^b, V. F. Mironov^ab

^a A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
^b Alexander Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russian Federation

Аннотация: A general approach to lupane monodesmosides containing a C-28 phosphonioalkyl group is based on the initial glycosylation of triterpene acid w-haloalkyl esters at the C-3 position. The subsequent phosphorylation with triphenylphosphine and deprotection in the carbohydrate moiety finalize the synthesis.

Ключевые слова: lupane, triterpenes, betulinic acid, saponins, glycoside, mannopyranose, glycosylation, phosphonium salts.

Язык публикации: английский

DOI: 10.1016/j.mencom.2021.01.034