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JOURNALS // Computer Optics // Archive

Computer Optics, 2020 Volume 44, Issue 5, Pages 809–820 (Mi co851)

This article is cited in 6 papers

NUMERICAL METHODS AND DATA ANALYSIS

Methods of mathematical modeling of fundus laser exposure for therapeutic effect evaluation

A. S. Shirokanevab, A. S. Kibitkinaa, N. Yu. Ilyasovaba, A. A. Degtyaryova

a Samara National Research University, 443086, Samara, Russia, Moskovskoye Shosse 34
b IPSI RAS – Branch of the FSRC "Crystallography and Photonics" RAS, 443001, Samara, Russia, Molodogvardeyskaya 151

Abstract: When laser coagulation of eye retina is carried out, the laser beam is directed to target retinal areas selected by an ophthalmologist. The exposure to laser light produces a photocoagulate. When using laser coagulation, the main problem is selecting both the laser exposure areas that would cover all pathological zones and the laser exposure parameters to prevent retina damage. Any patient has an individual fundus structure. The individual structure of pathological and anatomical elements must be taken into account to achieve the desired therapeutic effect.
The formation of coagulates in all hemorrhage-affected areas results in the desired therapeutic effect. The vascular layer must be heated to a sufficient temperature to form a coagulate. Such an effect can be predicted using mathematical modeling of laser exposure.
In this paper, we consider methods of mathematical modeling of laser exposure based on the solution of a heat equation. The methods are compared in terms of their computational complexity and solution stability. An analysis of the possibility of predicting the therapeutic effect using methods of mathematical modeling of laser exposure is carried out.

Keywords: diabetic retinopathy, laser coagulation, therapeutic effect, mathematical modeling, heat equation, initial and boundary conditions.

Received: 25.06.2020
Accepted: 08.07.2020

DOI: 10.18287/2412-6179-CO-760



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