S. Yu. Kovalenko, A. S. Bratus', “The task of search viable therapy strategy for a mathematical spatial cancer model”, Computer Research and Modeling, 2013, Volume 5, Issue 4,Pages <nobr>749

ANALYSIS AND MODELING OF COMPLEX LIVING SYSTEMS

The task of search viable therapy strategy for a mathematical spatial cancer model

S. Yu. Kovalenko^a, A. S. Bratus'^b

^a Federal Science and Clinical Center of the Federal Medical and Biological Agency, 28 Orehovuy boulevard, Moscow, 115682, Russia
^b Moscow State University, Leninskie goru 1/526, Moscow, 119991, Russia

Abstract: This paper is devoted to the analysis of the partial mathematical model describing the process of growth and spread of malignant and normal cells under the influence of chemotherapy. We found the periodic therapy regime, conditions the existence of this regime and suggest the search algorithm of this regime. This paper also includes the examples of simulation and the set of parameter values.

Keywords: viable task, glioma, periodic therapy regime.

UDC: 519.8

Received: 15.09.2013
Revised: 24.10.2013

DOI: 10.20537/2076-7633-2013-5-4-749-765