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JOURNALS // Computer Research and Modeling // Archive

Computer Research and Modeling, 2009 Volume 1, Issue 2, Pages 209–215 (Mi crm638)

This article is cited in 1 paper

ANALYSIS AND MODELING OF COMPLEX LIVING SYSTEMS

Nonlinear waves in the DNA molecules containing a boundary between two homogeneous regions

L. V. Yakushevicha, A. V. Savinb, L. I. Manevichb

a Institute of Cell Biophysics, Institutskaya str. 3, Puschino, Moscow Region, 142290, Russia
b Semenov Institute of Chemical Physics, Kosygin str. 4, Moscow, 119991, Russia

Abstract: Propagation of nonlinear conformational waves through the boundary dividing the double polynucleotide chain into two different homogeneous regions is investigated. Calculations are made in the frameworks of the DNA model which takes into account the difference in mass of nitrous bases and the difference in distances between sugar-phosphate chain and the centers of mass of bases which are connected with the chain by $\beta$-glycoside bond $\mathrm{C}_1$$\mathrm{N}$. We consider different possible combinations of homogeneous regions placed on the right and on the left from the boundary, and we calculate the changes of the nonlinear wave velocity $(v)$ and size $(d)$ of the nonlinear waves due to overcoming the boundary.

Keywords: DNA, wave propagation, polynucleotide chain.

Received: 26.11.2008

DOI: 10.20537/2076-7633-2009-1-2-209-215



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