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JOURNALS // Intelligent systems. Theory and applications // Archive

Intelligent systems. Theory and applications, 2022 Volume 26, Issue 1, Pages 306–310 (Mi ista375)

Part 7. Neuromorphic artificial intelligence and cognitive systems

Comparison of c-fos and arc genes expression patterns in mouse brain after contextual associative memory formation and retrieval

L. S. Kazanskayaa, O. I. Ivashkinabc, K. A. Toropovacb, K. V. Anokhinca

a NII of Normal Physiology of RAMS
b NRC "Kurchatov Institute"
c Institute of Advanced Brain Studies of Lomonosov MSU

Abstract: The study evaluated the induction of immediate early genes c-fos and Arc/Arg3.1 in mouse brain after contextual fear conditioning and after memory retrieval. It was shown that the induction of both genes in a number of brain structures occurs after this exposure, however, only 30% of neurons simultaneously express both genes.

Keywords: immediate early genes, c-Fos, Arc, neuroplastisity, engram.



© Steklov Math. Inst. of RAS, 2024