Composite nonwoven materials with microparticles for regenerative surgery

Composite nonwoven materials with different medical supplements are widely used for regenerative surgery. Majority of these medicines are cytotoxic, therefore precise drug delivery is necessary to decrease toxic effects. We propose novel polymer nanofibrous material impregnated by core–shell microstructures that can provide targeted and controllable release of encapsulated drugs. This biodegradable scaffold system was fabricated using mixing of calcium carbonate microparticles with chitosan solutions followed by electrospinning method.