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Zhurnal Tekhnicheskoi Fiziki, 2021 Volume 91, Issue 12, Pages 2059–2066 (Mi jtf4852)

This article is cited in 3 papers

Physics for sciences of life

Electrical stimulation of human dermal fibroblasts on conducting matrix

K. A. Kolbeab, M. A. Shishovab, I. Yu. Sapurinab, N. V. Smirnovaab, V. V. Kodolova-Chukhontsevaa, E. N. Dresvyaninaa, A. M. Kamalova, V. E. Yudinab

a Peter the Great St. Petersburg Polytechnic University
b Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg

Abstract: Conducting composite based on biocompatible chitosan and single wall carbon nanotubes was used as a matrix for electrical stimulation of human fibroblasts. Parameters of ionic and electronic currents passing through the matrix upon applying cyclic potentials ($\pm$100 mV) were studied; the scaffold demonstrated high stability in the course of prolonged electric cycling. It was shown that preliminary electrical stimulation facilitated proliferative activity of human dermal fibroblasts in comparison to that of intact cells.

Keywords: chitosan/carbon nanotube composite, electrical stimulation, dermal fibroblasts.

Received: 27.05.2021
Revised: 10.08.2021
Accepted: 11.08.2021

DOI: 10.21883/JTF.2021.12.51772.160-21



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