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Zhurnal Tekhnicheskoi Fiziki, 2018 Volume 88, Issue 9, Pages 1348–1354 (Mi jtf5816)

This article is cited in 2 papers

Physical approaches and problems of data interpretation in the life sciences

Viability of different types of cells cultivated on the surface of medical electret

O. I. Aleksandrovaa, S. A. Aleksandrovaa, V. P. Khomutovb, M. S. Morgunovb, M. I. Blinovaa

a Institute of Cytology Russian Academy of Science, St. Petersburg
b OOO Medel, St. Petersburg

Abstract: The effect of the electric field of a medical electret on the basis of tantalum pentoxide (Ta$_2$O$_5$) on the viability of human fibroblasts, multipotent mesenchymal stromal bone marrow cells, osteocytes, and chondrocytes cultivated on the surface of tantalum orthopedic implants with an electret coating was studied in vitro. Using the methods of photocolorimetic analysis and scanning electron microscopy, difference in the metabolic activity and cell morphology, in the character of the cell attachment to the implants and distribution by their surface, associated with the value and character of the electric charge distribution on the surface of these implants and the type of cellular test systems, were detected. Unclear mechanisms of the effect of the electric field of medical electrets on the functional activity of different types of the organism cell and tissues dictate the need for further experimental developments and fundamental studies in this field.

Keywords: Bone Marrow Mesenchymal Stromal Cells, Osteocytes, Multipotent Mesenchymal Stromal Cells (MMSC), Tantalum Disk, Linear Charge Distribution.

Received: 09.02.2018

DOI: 10.21883/JTF.2018.09.46419.58-18


 English version:
Technical Physics, 2018, 63:9, 1304–1310

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