Phase synchronization between time signals extracted from biological data

The task is to determine the indices of phase synchronization between biological data extracted from neuronal activity and fluctuations in blood pressure and respiration, based on the calculation of instantaneous frequencies and phases using the synchrosqueezed wavelet analysis. Differences in synchronization indices between the analyzed data in two groups of rats (the control group and the group with experimentally induced colitis) were revealed. Pain exposure was found to be associated with frequency adjustment of the variability of the neuronal activity or the blood pressure, followed by the onset of phase synchronization.