Mathematical model of the humoral immune response: focusing on Th17 autoimmunity

This work is devoted to development of mathematical model, describing processes of Th and B lymphocyte proliferation and differentiation, as well as IFN-$\gamma$, IL-2, IL-4 and IL-21 cytokine secretion. New approaches are suggested, allowing more accurate modelling. Special attention paid to Th17 lymphocyte impact to effect of plasma cells and IgM and IgG antibody level increasing.