V. G. Fedoseeva, E. A. Verochkina, L. I. Larina, E. V. Kondrashov, I. B. Rosentsveig, N. V. Vchislo, “Novel capto-dative (Z,E)-2-(alkylthio)alk-2-en-4-ynals: synthesis and heterocyclization”, Mendeleev Commun., 2021, Volume 31, Issue 6,Pages 856

This article is cited in 5 papers

Communications

Novel capto-dative (Z,E)-2-(alkylthio)alk-2-en-4-ynals: synthesis and heterocyclization

V. G. Fedoseeva, E. A. Verochkina, L. I. Larina, E. V. Kondrashov, I. B. Rosentsveig, N. V. Vchislo

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, Irkutsk, Russian Federation

Abstract: An efficient synthesis of new (Z,E)-2-(alkylthio)alk-2-en-4-ynals by aldol condensation reaction of ynals with (alkylthio)-acetaldehydes using NaOH/DMF system has been developed.The reaction of these products with N,N-diphenylethylene-diamine and p-tosylmethyl isocyanide proceeds at the carbonyl group to form the corresponding imidazolidine and oxazole derivatives.

Keywords: Α-enals, enynals, aldol condensation, heterocyclization, oxazoles, imidazolidines, organogermanium compounds.

Language: English

DOI: 10.1016/j.mencom.2021.11.029

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