Mendeleev Commun., 2021 Volume 31, Issue 6, Pages 867–868
(Mi mendc1070)
This article is cited in
1 paper
Communications
Synthesis of a tripeptide biomarker of exposure to sulfur mustard for support of OPCW biomedical proficiency tests
V. V. Abzianidze ,
Yu. V. Chelusnova ,
G. V. Karakashev ,
D. M. Kochura ,
M. A. Leninskii ,
A. Yu. Gorbunov ,
M. D. Shachneva ,
D. V. Krivorotov ,
A. I. Ukolov Research Institute of Hygiene, Occupational Pathology and Human Ecology, Leningrad region, Russian Federation
Abstract:
S -[2-(2-Hydroxyethylthio)ethyl]-Cys-Pro-Phe (HETE–CPP) was synthesized in seven steps as a reference compound for the development of a procedure for its quantification in blood plasma in the OPCW biomedical proficiency tests.
Keywords:
OPCW, sulfur mustard, positive control, qualitative and quantitative analysis, collision-induced dissociation, sulfides, peptide synthesis, tripeptides.
Language: English
DOI:
10.1016/j.mencom.2021.11.033
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