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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2020 Volume 30, Issue 2, Pages 211–213 (Mi mendc1151)

This article is cited in 8 papers

Communications

Albumin aggregation promoted by protoporphyrin in vitro

N. Sh. Lebedeva, E. S. Yurina, Yu. A. Gubarev, A. N. Kiselev, S. A. Syrbu

G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russian Federation

Abstract: Protoporphyrin upon its binding with serum albumin changes its secondary structure due to the conversion of part of α helices into β-folding. This process results in the association of albumin globules in vitro.

Keywords: porphyrin, albumin, aggregation, UV-VIS spectroscopy, IR spectroscopy, fluorescence.

Language: English

DOI: 10.1016/j.mencom.2020.03.027



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