M. A. Ustimova, P. A. Chernikova, N. E. Shepel, Yu. V. Fedorov, O. A. Fedorova, “Effect of N-substituent in 4-styrylpyridinium dyes on their binding to DNA”, Mendeleev Commun., 2020, Volume 30, Issue 2,Pages <nobr>217

This article is cited in 7 papers

Communications

Effect of N-substituent in 4-styrylpyridinium dyes on their binding to DNA

M. A. Ustimova^a, P. A. Chernikova^a, N. E. Shepel^a, Yu. V. Fedorov^a, O. A. Fedorova^ab

^a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation

Abstract: 4-Styrylpyridinium dyes containing N-methyl and N-(3-pyridiniopropyl) substituents have been prepared and characterized by optical and CD spectroscopy. These compounds demonstrate affinity to calf thymus DNA, with dye–DNA binding mode being different for various N-substituents.

Keywords: styryl dye, DNA, intercalation, groove binding, fluorescent probes.

Language: English

DOI: 10.1016/j.mencom.2020.03.029

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