O. V. Pokidova, B. L. Psikha, A. Yu. Kormukhina, A. I. Kotelnikov, B. S. Fedorov, “Mechanism of the 2-ethyl-3-hydroxy-6-methylpyridinium 2-nitroxysuccinate reduction in nitrite-generating systems”, Mendeleev Commun., 2020, Volume 30, Issue 4,Pages <nobr>482

This article is cited in 2 papers

Communications

Mechanism of the 2-ethyl-3-hydroxy-6-methylpyridinium 2-nitroxysuccinate reduction in nitrite-generating systems

O. V. Pokidova^a, B. L. Psikha^a, A. Yu. Kormukhina^b, A. I. Kotelnikov^ab, B. S. Fedorov^a

^a Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
^b Department of Fundamental Physical and Chemical Engineering, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: The nitrite-generating activity of 2-ethyl-3-hydroxy-6-methylpyridinium 2-nitroxysuccinate as a promising NO-donor has been investigated in reactions with various reducing agents. Reduction of the NO-donor with cysteine was analyzed using a kinetic modeling method. The calculated rate constants satisfactorily describe the experimental data, thereby confirming the proposed reaction mechanism.

Keywords: organic nitrate, thionitrate, cysteine, Griess method, nitrite ion.

Language: English

DOI: 10.1016/j.mencom.2020.07.025