A. S. Kritchenkov, A. I. Kurachenkov, A. R. Egorov, N. Z. Yagafarov, E. A. Fortalnova, N. N. Lobanov, A. P. Dysin, A. S. Khomik, V. N. Khrustalev, “Novel zinc(II)/chitosan-based composite: ultrasound-assisted synthesis, catalytic and antibacterial activity”, Mendeleev Commun., 2020, Volume 30, Issue 5,Pages <nobr>642

This article is cited in 7 papers

Communications

Novel zinc(II)/chitosan-based composite: ultrasound-assisted synthesis, catalytic and antibacterial activity

A. S. Kritchenkov^abc, A. I. Kurachenkov^a, A. R. Egorov^a, N. Z. Yagafarov^ad, E. A. Fortalnova^a, N. N. Lobanov^a, A. P. Dysin^b, A. S. Khomik^a, V. N. Khrustalev^ae

^a Peoples Friendship University of Russia (RUDN University), Moscow, Russian Federation
^b St. Petersburg National Research University of Information Technologies, Mechanics and Optics, St. Petersburg, Russian Federation
^c Institute of Technical Acoustics, National Academy of Sciences of Belarus, Vitebsk, Republic of Belarus
^d N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
^e N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: Ultrasonic treatment of the reaction between chitosan and aromatic aldehyde, 4-formyl-3-hydroxy-5-hydroxymethyl-1,2-dimethylpyridin-1-ium iodide, resulted in its significant acceleration and increase in degree of derivatization. The CH=N bond of the prepared Schiff base was reduced, and the formed polymeric material was converted into the corresponding zinc(II) composite by treatment with ZnCl₂ and NaOH. The obtained composite is non-toxic, possesses high antibacterial activity and can be employed as the catalyst in the Mannich reaction between benzaldehyde, phenylacetylene and piperidine.

Keywords: chitosan, zinc(II) complexes, antibacterial activity, catalytic activity, Mannich reaction, propargylic amines, pyridoxal.

Language: English

DOI: 10.1016/j.mencom.2020.09.030

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