A. N. Vereshchagin, N. A. Frolov, A. S. Pakina, K. A. Hansford, M. P. Egorov, “Synthesis and biological evaluation of novel bispyridinium salts containing naphthalene-2,7-diylbis(oxy) spacer”, Mendeleev Commun., 2020, Volume 30, Issue 6,Pages <nobr>703

This article is cited in 8 papers

Communications

Synthesis and biological evaluation of novel bispyridinium salts containing naphthalene-2,7-diylbis(oxy) spacer

A. N. Vereshchagin^a, N. A. Frolov^a, A. S. Pakina^ab, K. A. Hansford^c, M. P. Egorov^a

^a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
^c Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

Abstract: Novel five bispyridinium salts based on a naphthalene-2,7-diylbis(oxy) spacer were synthesized. The obtained compounds showed stronger biological activity against five strains of bacteria and two fungi as compared to modern biocides used in the pharmaceutical market.

Keywords: bis-quaternary ammonium compounds, pyridinium salts, biological activity, antibacterial agents, antifungal activity.

Language: English

DOI: 10.1016/j.mencom.2020.11.004

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