Structure and properties of hydrogels based on sodium alginate and synthetic polyacids

Hydrogels based on interpolymer complexes of sodium alginate and different synthetic polyacids were prepared, and the effect of structure and composition of the complexes on their properties was studied. The microstructure of the hydrogels was investigated by SEM and AFM to understand correlations between hydrogel structures and their behaviors and properties. The hydrogel surfaces were influenced by the polyacid structure and gel preparation method. The hydrogel morphology, swelling, and drug release rate were discussed.