N. A. Kuznetsov, O. A. Bogomolova, I. A. Koblov, A. V. Samet, V. V. Semenov, “Synthesis of 3,4-diarylisoxazoline <em>N</em>-oxides from nitrostilbenes and nitroacetates”, Mendeleev Commun., 2025, Volume 35, Issue 1,Pages <nobr>22

Communications

Synthesis of 3,4-diarylisoxazoline N-oxides from nitrostilbenes and nitroacetates

N. A. Kuznetsov^ab, O. A. Bogomolova^b, I. A. Koblov^a, A. V. Samet^a, V. V. Semenov^a

^a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
^b D. I. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russian Federation

Abstract: A base-catalyzed reaction of nitrostilbenes with alkyl nitroacetates proceeds regioselectively to afford 3,4-diarylisoxazoline N-oxides as sole or major products. In some cases small amounts of 4,5-diarylisoxazoline N-oxides were formed as side products.

Keywords: nitrostilbenes, alkyl nitroacetates, 3,4-diarylisoxazoline N-oxides, 4,5-diarylisoxazoline N-oxides, pyridinium ylides.

Received: 05.08.2024
Accepted: 11.09.2024

Language: English

DOI: 10.71267/mencom.7584

	*Supplementary materials:*
		Supplementary_data_1.pdf	871.6 Kb