A. M. Zhirkova, K. V. Zaitsev, A. A. Prishchenko, M. V. Vasiliev, M. V. Kotova, K. A. Uschakova, L. A. Martirosyan, I. V. Perminova, “Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids”, Mendeleev Commun., 2024, Volume 34, Issue 3,Pages <nobr>404

This article is cited in 1 paper

Communications

Simple and effective synthesis of functionalized (hydroxymethylene)bis(phosphonic) acids

A. M. Zhirkova, K. V. Zaitsev, A. A. Prishchenko, M. V. Vasiliev, M. V. Kotova, K. A. Uschakova, L. A. Martirosyan, I. V. Perminova

Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: ‘Technical’ tris(trimethylsilyl) phosphite, (Me₃SiO)₃P, as a mixture with (Me₃SiO)₂P(O)H and (Me₃SiO)₃P(O) (71 : 20 : 9) was obtained upon the action of (Me Si) NH on phosphorous acid H₃PO₃ in the presence of catalytic amount of Me₃SiCl. The action of this material on acid chlorides RC(O)Cl affords (hydroxymethylene)bis(phosphonic) acids RC(OH)[P(O)(OH)₂]₂ in preparative yields.

Keywords: organophosphorus compounds, tris(trimethylsilyl) phosphite, hexamethyldisilazane, phosphorous acid, carboxylic acid chlorides, bis(phosphonic) acids, NMR spectroscopy.

Language: English

DOI: 10.1016/j.mencom.2024.04.029

	*Supplementary materials:*
		Supplementary_data_1.pdf	743.2 Kb