A. S. Polyakova, P. A. Panchenko, A. V. Efremenko, A. V. Feofanov, Yu. V. Fedorov, O. A. Fedorova, “A naphthalimide-based fluorescent and colorimetric probe for the detection of mercury(II) ions in aqueous solutions and in living cells”, Mendeleev Commun., 2024, Volume 34, Issue 3,Pages <nobr>418

This article is cited in 1 paper

Communications

A naphthalimide-based fluorescent and colorimetric probe for the detection of mercury(II) ions in aqueous solutions and in living cells

A. S. Polyakova^a, P. A. Panchenko^ab, A. V. Efremenko^c, A. V. Feofanov^cd, Yu. V. Fedorov^a, O. A. Fedorova^ab

^a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
^c M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^d Department of Biology, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: A novel derivative of 4-styryl-1,8-naphthalimide containing an N-arylazadithia-15-crown-5-ether moiety as a receptor exhibited a hypsochromic shift with simultaneous fluorescence quenching upon complexation with the mercury(II) cation. The compound is suggested as a selective fluorescent chemosensor for the detection of Hg²⁺ in aqueous solutions and in HEK 293 cells.

Keywords: sensor, mercury cation, fluorescence imaging, HEK 293 cells, intramolecular charge transfer, hypsochromic shift, azadithia- crown compounds, 1,8-naphthalimide, Heck reaction.

Language: English

DOI: 10.1016/j.mencom.2024.04.034

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