R. R. Yaubasarova, V. A. Kokorekin, G. V. Ramenskaya, V. A. Petrosyan, “Double electrooxidative C–H functionalization of (het)arenes with thiocyanate and 4-nitropyrazolate ions”, Mendeleev Commun., 2019, Volume 29, Issue 3,Pages <nobr>334

This article is cited in 18 papers

Communications

Double electrooxidative C–H functionalization of (het)arenes with thiocyanate and 4-nitropyrazolate ions

R. R. Yaubasarova^a, V. A. Kokorekin^abc, G. V. Ramenskaya^b, V. A. Petrosyan^a

^a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation
^c All-Russian Research Institute of Phytopathology, Bol'shiye Vyazemy, Moscow Region, Russian Federation

Abstract: The double anodic C–H functionalization of N-methyl-1H-pyrrole and N,N-dimethylaniline using both thiocyanate and 4-nitro-1H-pyrazolate ions as nucleophiles has been accomplished for the first time. The mild reaction conditions and considerable pharmacological activity of the target products make such C–S and C–N coupling strategy to be highly attractive for further applications.

Language: English

DOI: 10.1016/j.mencom.2019.05.032