O. B. Bondarenko, Z. M. Garaev, A. I. Komarov, L. I. Kuznetsova, S. V. Gutorova, D. A. Skvortsov, N. V. Zyk, “Nitrosylsulfuric acid in the synthesis of 5-chloroisoxazoles from 1,1-dichlorocyclopropanes”, Mendeleev Commun., 2019, Volume 29, Issue 4,Pages <nobr>419

This article is cited in 3 papers

Communications

Nitrosylsulfuric acid in the synthesis of 5-chloroisoxazoles from 1,1-dichlorocyclopropanes

O. B. Bondarenko, Z. M. Garaev, A. I. Komarov, L. I. Kuznetsova, S. V. Gutorova, D. A. Skvortsov, N. V. Zyk

Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: Nitrosylsulfuric acid is shown to be a usable reagent for the synthesis of 5-chloroisoxazoles from readily available 1,1-di-chlorocyclopropanes via nitrosation–heterocyclization reaction. A cytotoxicity of some of the prepared 5-chloroisoxazoles towards MCF7, A549, HEK293T and VA13 cell lines was evaluated.

Language: English

DOI: 10.1016/j.mencom.2019.07.021