E. D. Mordvinova, M. V. Parkhats, Y. Chen, I. P. Pozdnyakov, “Intermolecular interactions between natural humic substances and tricyclic antidepressants”, Mendeleev Commun., 2019, Volume 29, Issue 4,Pages <nobr>426

This article is cited in 3 papers

Communications

Intermolecular interactions between natural humic substances and tricyclic antidepressants

E. D. Mordvinova^ab, M. V. Parkhats^c, Y. Chen^d, I. P. Pozdnyakov^ab

^a Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russian Federation
^b V.V. Voevodsky Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
^c B.I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk, Belarus
^d Huazhong University of Science and Technology, Wuhan, China

Abstract: Intermolecular interactions between humic substances (HSs) and the tricyclic antidepressants (TAs) amitriptyline, nortriptyline, imipramine and desipramine were detected for the first time by fluorescence spectroscopy. Two simplest models assuming coordination of one or two of TA molecules at the binding centers of HSs were proposed to explain the photodegradation of TAs caused by sunlight photolysis of humic substances.

Language: English

DOI: 10.1016/j.mencom.2019.07.024

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