RUS  ENG
Full version
JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2024 Volume 34, Issue 3, Pages 450–452 (Mi mendc157)

This article is cited in 1 paper

Communications

Hydrophilic interaction liquid chromatography: mixed-mode with advanced π–π selectivity realization

E. V. Upyrenko, D. A. Kurgachev

Department of Chemistry, National Research Tomsk State University, Tomsk, Russian Federation

Abstract: Aprotic polar solvents do not suppress π–π interactions and polar stationary phase containing aromatic groups. The THF additives to MeCN/phosphate buffer mobile phase for hydrophilic interaction liquid chromatography operating in a mixed-mode eliminate lipophilic compounds interference saving unique π – π selectivity.

Keywords: hydrophilic interaction liquid chromatography, acetonitrile, tetrahydrofuran, pentafluorophenyl stationary phase, π–π interactions, lipophilic matrix.

Language: English

DOI: 10.1016/j.mencom.2024.04.044



© Steklov Math. Inst. of RAS, 2025