A. D. Zorina, N. S. Nikiforova, V. V. Zarubaev, S. A. Marchenko, S. I. Selivanov, G. L. Starova, A. R. Mehtiev, E. I. Rodionov, A. A. Rodionova, R. E. Trifonov, “Synthesis, structure and <i>in vitro</i> biological evaluation of new lupane and dammarane triterpenoids fused with pyrazine heterocycle”, Mendeleev Commun., 2019, Volume 29, Issue 5,Pages <nobr>500

This article is cited in 10 papers

Communications

Synthesis, structure and in vitro biological evaluation of new lupane and dammarane triterpenoids fused with pyrazine heterocycle

A. D. Zorina^a, N. S. Nikiforova^a, V. V. Zarubaev^b, S. A. Marchenko^a, S. I. Selivanov^a, G. L. Starova^a, A. R. Mehtiev^c, E. I. Rodionov^a, A. A. Rodionova^a, R. E. Trifonov^a

^a St. Petersburg State University, St. Petersburg, Russian Federation
^b St. Petersburg Pasteur Institute, St. Petersburg, Russian Federation
^c V.N. Orekhovich Institute of Biomedical Chemistry, Moscow, Russian Federation

Abstract: Derivatives of natural lupenone, dipterocarpol, alnincanone and semisynthetic dipterocarpol lactone fused with pyrazine heterocycle along C²–C³ positions were obtained by the Willgerodt–Kindler reaction, X-ray analysis having been used for the structure identification. Anti-influenza and anti-proliferative activities of the compounds obtained were estimated.

Language: English

DOI: 10.1016/j.mencom.2019.09.007

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