M. A. Khomutov, A. O. Chizhov, S. N. Kochetkov, A. R. Khomutov, “Synthesis of (<i>R</i>)- and (<i>S</i>)-isomers of 2-methylspermidine”, Mendeleev Commun., 2019, Volume 29, Issue 6,Pages <nobr>678–679</nobr>

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Mendeleev Commun., 2019 Volume 29, Issue 6, Pages 678–679 (Mi mendc1628)

Communications

Synthesis of (R)- and (S)-isomers of 2-methylspermidine

M. A. Khomutov^a, A. O. Chizhov^b, S. N. Kochetkov^a, A. R. Khomutov^a

^a V.A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russian Federation
^b N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: The title compounds, (R)- and (S)-isomers of 1,8-diamino-2-methyl-4-azaoctane, were prepared from commercially available enantiomers of 3-bromo-2-methylpropan-1-ol, each in six steps and good overall yields.

Language: English

DOI: 10.1016/j.mencom.2019.11.025

Fulltext: PDF file (232 kB)

	*Supplementary materials:*
		Supplementary_data_1.pdf	836.4 Kb

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