O. A. Shemyakina, O. G. Volostnykh, A. V. Stepanov, A. G. Mal'kina, I. A. Ushakov, K. A. Apartsin, V. V. Kireeva, B. A. Trofimov, “DBU as a scaffold for the synthesis of [1,3]oxazolo[2’,3’ : 2,3]pyrimido-[1,2-a]azepines: annulation with aromatic cyanopropargylic alcohols”, Mendeleev Commun., 2018, Volume 28, Issue 2,Pages 128

This article is cited in 9 papers

Communications

DBU as a scaffold for the synthesis of [1,3]oxazolo[2’,3’ : 2,3]pyrimido-[1,2-a]azepines: annulation with aromatic cyanopropargylic alcohols

O. A. Shemyakina^a, O. G. Volostnykh^a, A. V. Stepanov^a, A. G. Mal'kina^a, I. A. Ushakov^a, K. A. Apartsin^bc, V. V. Kireeva^c, B. A. Trofimov^a

^a A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, Irkutsk, Russian Federation
^b Irkutsk Scientific Center of Surgery and Traumatology, Irkutsk, Russian Federation
^c Biomedical Research and Technology Department of the Irkutsk Scientific Center, Siberian Branch of the Russian Academy of Sciences, Irkutsk, Russian Federation

Abstract: Organic superbase DBU, 1,8-diazabicyclo[5.4.0]undec-7-ene, readily annulated with aromatic cyanopropargylic alcohols nder mild conditions (CH₂Cl₂, 20–25 °C, 30 min) to afford new cyanomethylideneperhydro[1,3]oxazolo[2’,3’:2,3]pyrimido-,2-a]azepines.

Language: English

DOI: 10.1016/j.mencom.2018.03.004

	*Supplementary materials:*
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