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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2018 Volume 28, Issue 2, Pages 195–197 (Mi mendc1711)

This article is cited in 3 papers

Communications

Synthesis of potential anti-Trypanosoma cruzi azole-naftifine analogues by azide–alkyne click reaction

C. H. Zacchia, S. S. Federighib, F. R. Gadelhab, F. T. Martinsc, R. B. Alvesa, Â. de Fátimaa

a Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
b Universidade Estadual de Campinas, Campinas, São Paulo, Brazil
c Universidade Federal de Goias, Goiânia, Brazil

Abstract: Twenty novel azole-naftifine analogues were obtained using azide–alkyne click reaction. Five of them were more potent than the positive control naftifine revealing an unprecedented antiproliferative effects against Trypanosoma cruzi.

Language: English

DOI: 10.1016/j.mencom.2018.03.029



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