S. S. Kuvshinova, A. F. Smol'yakov, D. V. Vorobyeva, S. N. Osipov, D. A. Loginov, “CF3-Carbenoid functionalization of N-(pyrimidin-2-yl)indole catalyzed by cobalt complexes: Ligand control of selectivity”, Mendeleev Commun., 2018, Volume 28, Issue 4,Pages <nobr>359

This article is cited in 13 papers

Communications

CF3-Carbenoid functionalization of N-(pyrimidin-2-yl)indole catalyzed by cobalt complexes: Ligand control of selectivity

S. S. Kuvshinova^a, A. F. Smol'yakov^ab, D. V. Vorobyeva^a, S. N. Osipov^a, D. A. Loginov^a

^a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^b Peoples Friendship University of Russia (RUDN University), Moscow, Russian Federation

Abstract: The carbonyl cobalt complex Cp*Co(CO)I₂ catalyzes carbenoid Co alkylation of N-(pyrimidin-2-yl)indole with methyl 3,3,3-trifluoro-2-diazopropionate regioselectively giving 2-substituted indole, while the N,N’-ligated cations [CpCo(L)I]⁺ (L=bipy, phen) provide 3-substitution exclusively. The structure of [CpCo(phen)I]PF₆ was investigated by X-ray diffraction.

Language: English

DOI: 10.1016/j.mencom.2018.07.005