RUS  ENG
Full version
JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2017 Volume 27, Issue 1, Pages 85–87 (Mi mendc1904)

This article is cited in 6 papers

Communications

Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties

M. P. Paramonovaa, A. L. Khandazhinskayab, K. L. Seley-Radtkec, M. S. Novikova

a Volgograd State Medical University, Volgograd, Russian Federation
b V.A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russian Federation
c Department of Chemistry and Biochemistry, University of Maryland, Maryland, USA

Abstract: The title compounds were prepared from 1-[5-(4-bromophenoxy) pentyl]uracil by the introduction of N-arylacetamide moiety at the 3-position, the better approach involving the use of N-aryl-2-chloroacetamides as the reactants. Antiviral activity of the obtained compounds was estimated.

Language: English

DOI: 10.1016/j.mencom.2017.01.027



© Steklov Math. Inst. of RAS, 2025