V. A. D'yakonov, A. A. Makarov, L. U. Dzhemileva, E. N. Andreev, U. M. Dzhemilev, “The first total synthesis of lembehyne B”, Mendeleev Commun., 2017, Volume 27, Issue 2,Pages <nobr>122

This article is cited in 13 papers

Communications

The first total synthesis of lembehyne B

V. A. D'yakonov, A. A. Makarov, L. U. Dzhemileva, E. N. Andreev, U. M. Dzhemilev

Institute of Petrochemistry and Catalysis, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation

Abstract: The total synthesis of lembehyne B was accomplished in five steps in 51% total yield. The cross-cyclomagnesiation of two allenic components, nonadeca-1,2-diene and pentadeca-13,14-dien-1-ol tetrahydropyranyl ether, with EtMgBr in the presence of Mg and Cp₂TiCl₂ catalyst (10 mol%) was used in the key step of the synthesis.

Language: English

DOI: 10.1016/j.mencom.2017.03.004

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