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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2017 Volume 27, Issue 3, Pages 283–284 (Mi mendc1969)

This article is cited in 6 papers

Communications

2-Aminopyrimidines in just two steps from ketones, acetylenes and guanidine via β,γ enones

E. Yu. Schmidt, I. V. Tatarinova, E. V. Ivanova, B. A. Trofimov

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, Irkutsk, Russian Federation

Abstract: Available β,γ-enones, the products of nucleophilic addition of ketones to phenylacetylene, react with guanidine in the KOH / DMSO system at 70°C to give 2-aminopyrimidines in up to 72% yield.

Language: English

DOI: 10.1016/j.mencom.2017.05.022



© Steklov Math. Inst. of RAS, 2025