Zh. V. Chirkova, M. V. Kabanova, S. I. Filimonov, I. G. Abramov, A. V. Samet, G. A. Stashina, “The C-3 chlorination of 2-aryl-1-hydroxyindoles”, Mendeleev Commun., 2017, Volume 27, Issue 5,Pages <nobr>498

This article is cited in 4 papers

Communications

The C-3 chlorination of 2-aryl-1-hydroxyindoles

Zh. V. Chirkova^a, M. V. Kabanova^a, S. I. Filimonov^a, I. G. Abramov^a, A. V. Samet^b, G. A. Stashina^b

^a Department of Organic Chemistry, Yaroslavl State Technical University, Yaroslavl, Russian Federation
^b N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: Chlorination of 2-aryl-1-hydroxyindole-5,6-dicarbonitriles with N-chlorosuccinimide affords previously unknown 3,3-dichloro-3H-indole 1-oxides instead of the expected 1-hydroxy- 3-chloroindoles. The latter can be prepared in good yields by treatment of the above 3,3-dichloro-3H-indole 1-oxides with piperidine in ethanol.

Language: English

DOI: 10.1016/j.mencom.2017.09.023