Z. R. Valiullina, V. A. Akhmet'yanova, N. S. Vostrikov, M. S. Miftakhov, “A short synthesis of the carbocyclic core of Entecavir from Corey lactone”, Mendeleev Commun., 2016, Volume 26, Issue 1,Pages <nobr>9

This article is cited in 6 papers

Communications

A short synthesis of the carbocyclic core of Entecavir from Corey lactone

Z. R. Valiullina, V. A. Akhmet'yanova, N. S. Vostrikov, M. S. Miftakhov

Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation

Abstract: The readily available Corey lactone was converted in three simple stages to tris-TBS-ether of (1R*,3R*,5S*)-1-hydroxymethyl-3,5-dihydroxy-2-methylidenecyclopentane – the protected carbocyclic core of Entecavir, one of the best medicines against hepatitis.

Language: English

DOI: 10.1016/j.mencom.2016.01.004