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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2016 Volume 26, Issue 1, Pages 72–74 (Mi mendc2115)

This article is cited in 20 papers

Communications

Reactions of chromone-3-carboxylic acid and chromone-3-carboxamides with cyanoacetic acid hydrazide

M. Yu. Korneva, V. S. Moshkina, O. S. Eltsovb, V. Ya. Sosnovskikha

a Institute of Natural Sciences and Mathematics, Ural Federal University, Ekaterinburg, Russian Federation
b Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation

Abstract: Chromone and chromone-3-carboxylic acid react with cyanoacetic acid hydrazide in the presence of NaOEt in boiling ethanol to form 6-(2-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3(2H)-one (58–62% yields), whereas reaction between chromone-3-carboxamides and cyanoacetic acid hydrazide under the same conditions affords 1-amino-2,5-dioxo-2,5-dihydro-1H-chromeno[4,3-b]pyridine-3-carbonitriles (50–67% yields).

Language: English

DOI: 10.1016/j.mencom.2016.01.028



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