A. V. Trifonov, R. K. Bagautdinova, L. K. Kibardina, M. A. Pudovik, A. P. Lyubina, A. D. Voloshina, A. S. Gazizov, A. R. Burilov, “New triazole-containing 7-azacoumarin-3-carboxamides: synthesis and biological properties”, Mendeleev Commun., 2024, Volume 34, Issue 5,Pages <nobr>688

Communications

New triazole-containing 7-azacoumarin-3-carboxamides: synthesis and biological properties

A. V. Trifonov, R. K. Bagautdinova, L. K. Kibardina, M. A. Pudovik, A. P. Lyubina, A. D. Voloshina, A. S. Gazizov, A. R. Burilov

A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation

Abstract: New azidomethyl-substituted 7-azacoumarin-3-carbox- amides were converted into the corresponding 1,2,3-triazole hybrids by the copper-catalyzed click reaction with phenyl- acetylene. Cytotoxicity and antimicrobial activity were evaluated, and leading compounds were identified.

Keywords: azacoumarins, azides, triazoles, cyloaddition reactions, cytotoxicity, antimicrobial activity.

Language: English

DOI: 10.1016/j.mencom.2024.09.020

	*Supplementary materials:*
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