M. N. Elinson, F. V. Ryzhkov, A. N. Vereshchagin, T. A. Zaimovskaya, V. A. Korolev, M. P. Egorov, “Multicomponent assembling of isatins, malononitrile and 4-hydroxy-6-methylpyridin-2(1H)-ones: one-pot efficient approach to privileged spiro[indoline-3,4’-pyrano[3,2-c]pyridine]-2,5’(6’H)-dione scaffold”, Mendeleev Commun., 2016, Volume 26, Issue 5,Pages 399

This article is cited in 18 papers

Communications

Multicomponent assembling of isatins, malononitrile and 4-hydroxy-6-methylpyridin-2(1H)-ones: one-pot efficient approach to privileged spiro[indoline-3,4’-pyrano[3,2-c]pyridine]-2,5’(6’H)-dione scaffold

M. N. Elinson^a, F. V. Ryzhkov^a, A. N. Vereshchagin^a, T. A. Zaimovskaya^b, V. A. Korolev^a, M. P. Egorov^a

^a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: The new one-pot multicomponent assembling of isatins, malononitrile and 4 hydroxy-6-methylpyridin-2(1H)-ones into previously unknown 2’-amino-7’-methyl-2,5’-dioxo-5’,6’-dihydrospiro[indoline-3,4’-pyrano[3,2-c]pyridine]-3’-carbonitriles in 80–98% yields has been accomplished by their reflux in ethanol in the presence of sodium acetate.

Language: English

DOI: 10.1016/j.mencom.2016.09.011

	*Supplementary materials:*
		Supplementary_data_1.pdf	229.0 Kb