M. A. Novikov, A. Yu. Bobrova, A. A. Servetnik, E. I. Chernoburova, I. V. Zavarzin, Yu. V. Tomilov, “(XantPhos)AgBr as a cheap and readily available catalyst for the bromofluorocyclopropanation of electron-rich alkenes”, Mendeleev Commun., 2024, Volume 34, Issue 5,Pages <nobr>698

Communications

(XantPhos)AgBr as a cheap and readily available catalyst for the bromofluorocyclopropanation of electron-rich alkenes

M. A. Novikov, A. Yu. Bobrova, A. A. Servetnik, E. I. Chernoburova, I. V. Zavarzin, Yu. V. Tomilov

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: A silver phosphine complex (XantPhos)AgBr proved to be a cheap and readily accessible catalyst for bromofluoro- cyclopropanation of electron-rich alkenes with CFBr₂CO₂Na. Ozonolysis followed by treatment with NaHSO₃ was shown to be an effective protocol to purify gem-bromofluoro- cyclopropanes from unreacted alkene precursors.

Keywords: organofluorine compounds, cyclopropanes, bromofluorocarbene, silver catalysis, cyclopropanation, alkenes, ozonolysis.

Language: English

DOI: 10.1016/j.mencom.2024.09.023

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