K. Yu. Koltunov, A. N. Chernov, “BINOL Modification via SNAr Reactions with Pentafluoropyridine”, Mendeleev Commun., 2015, Volume 25, Issue 1,Pages 39

This article is cited in 6 papers

Communications

BINOL Modification via S_NAr Reactions with Pentafluoropyridine

K. Yu. Koltunov^ab, A. N. Chernov^bc

^a G.K. Boreskov Institute of Catalysis, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
^b Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russian Federation
^c V.S. Sobolev Institute of Geology and Mineralogy, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation

Abstract: (R)- and (S)-binaphthyl-2,2’-diols (BINOLs) smoothly react with pentafluoropyridine without racemization to give (R)- and (S)-2,2’- bis(tetrafluoropyridin-4-yloxy)-1,1’-binaphthyls. The 2(6)-positioned pyridine fluorine atoms can be replaced with amino moieties by reactions with amines.

Language: English

DOI: 10.1016/j.mencom.2015.01.014