A. V. Dezhenkov, M. V. Tankevich, E. D. Nikolskaya, I. P. Smirnov, G. E. Pozmogova, V. I. Shvets, Yu. G. Kirillova, “Synthesis of anionic peptide nucleic acid oligomers including γ-carboxyethyl thymine monomers”, Mendeleev Commun., 2015, Volume 25, Issue 1,Pages <nobr>47

This article is cited in 8 papers

Communications

Synthesis of anionic peptide nucleic acid oligomers including γ-carboxyethyl thymine monomers

A. V. Dezhenkov^a, M. V. Tankevich^a, E. D. Nikolskaya^a, I. P. Smirnov^b, G. E. Pozmogova^b, V. I. Shvets^a, Yu. G. Kirillova^a

^a M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation
^b Federal Research & Clinical Center of Physical-Chemical Medicine, Moscow, Russian Federation

Abstract: Synthesis of a modified thymine monomer based on l-Glu, solid phase synthesis of anionic peptide nucleic acid (PNA) oligomers containing the modified monomer and optimization of the deblocking procedure and cleavage conditions of the PNA oligomers from resin are accomplished.

Language: English

DOI: 10.1016/j.mencom.2015.01.017

	*Supplementary materials:*
		Supplementary_data_1.pdf	445.5 Kb